We study the molecular basis of persistence of one of the deadliest bacterial pathogens, Mycobacterium tuberculosis (Mtb), which kills over a million people every year. Mtb is the causative agent of human tuberculosis (TB), which has inflicted humans since the prehistoric era. The only possible treatment of TB is a multi-drug regimen administered over 6-9 months. Towards developing a shorter treatment regimen, the overarching goal of our research program is to decipher the molecular mechanisms of persistence of Mtb during an antibiotic exposure.

Please visit the Ojha Laboratory_[1] for details.