Published on New York State Department of Health, Wadsworth Center (https://wadsworth.org)

SCIRB Resources and Publications

Since 1998, SCIRB has supported neurological spinal cord injury scientific research projects from leading researchers within New York State to find a cure for spinal cord injuries. SCIRB has recommended approximately $170 million in research awards through 2025 to some of New York State's finest research teams. Research listed in the table below is a result of this funding.

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SCIRB Annual Reports

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External Publications

Since 1998, SCIRB has supported neurological spinal cord injury scientific research projects from leading researchers within New York State to find a cure for spinal cord injuries. SCIRB has recommended approximately $170 million in research awards through 2025 to some of New York State's finest research teams. Research listed in the table below is a result of this funding.

OrganizationInvestigator(s)Link/PubMed ID#Publication/Abstract Title
The Research Foundation for Downstate Health Sciences UniversityDura-Bernal, Salvadorhttps://papers.ssrn.com/sol3/papers.cfm?abstract_id=5525785[21]Corticospinal Neuron Subpopulations with Opposing Dynamics Converge to Shape Spinal Interneuron Computations
The Research Foundation for Downstate Health Sciences UniversityDura-Bernal, Salvadorhttps://www.abstractsonline.com/pp8/#!/21171/presentation/28029[22]Poster PSTR027.13/M14 - Motor cortex multiscale mechanistic model tuned to reproduce experimentally-recorded behavioral neural manifold derived from CEBRA
Icahn School of Medicine at Mount SinaiZou, Hongyan (Jenny)40566742[23]Generation of Plexin-B1 Conditional Knockout Mouse With CRISPR/Cas9 Technology
Icahn School of Medicine at Mount SinaiZou, Hongyan (Jenny)39747004[24]Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
Icahn School of Medicine at Mount SinaiZou, Hongyan (Jenny)41253783[25]Plexin-B1 safeguards astrocyte agility and glial alignment to facilitate wound corralling and axon pathfinding in mouse spinal cord injury model
Albany Research InstituteGupta, Disha and Wolpaw, Jonathan41439390[26]Methodological optimization for eliciting robust median nerve somatosensory evoked potentials for realtime single trial applications
Albany Research InstituteGupta, Disha41542597[27]A portable cortical evoked potential operant conditioning system (C-EPOCS): System development
Feinstein Institute for Medical ResearchBloom, Ona41189508[28]Toward convergence in spinal cord injury therapies: neuromodulation, pharmacology, imaging, and rehabilitation
Albany Research InstituteWolpaw, Jonathan39834745[29]SyncGenie: A programmable event synchronization device for neuroscience research
CUNY Staten IslandKnikou, Maria 41342931[30]Cervical and thoracolumbar transspinal stimulation at 0.3 Hz and 30 Hz facilitates neuronal excitability in healthy humans: a randomized cross-over study. 
Winifred Masterson Burke Medical Research InstituteHollis, Edmund41061042[31]Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury
The Feinstein Institutes For Medical ResearchBouton, Chadhttps://medrxiv.org/content/10.1101/2025.08.19.25330198v1.full-text[32]Restoring Cortically Mediated Movement and Sensation in Complete Tetraplegia. 
The Feinstein Institutes For Medical ResearchBouton, Chadhttps://www.medrxiv.org/content/10.1101/2025.09.21.25336267v1[33]Cortically Interfaced Human Avatar Enables Remote Volitional Grasp and Shared Discriminative Touch. 
Albany Research InstituteGupta, Disha40834866[34]Extracting robust single-trial somatosensory evoked potentials for non-invasive brain computer interfaces
Albany Research InstituteGupta, Disha40101361[35]Frequency dependence of cortical somatosensory evoked response to peripheral nerve stimulation with controlled afferent excitation
Albany Research InstituteGupta, Disha and Wolpaw, Jonathan40974412[36]Soleus H-reflex size versus stimulation rate in the presence of background muscle activity: a methodological study
Albany Research InstituteGupta, Disha40527334[37]Artifact-reference multivariate backward regression (ARMBR): a novel method for EEG blink artifact removal with minimal data requirements
University of RochesterBerk, Bradford40429643[38]PDE10A Inhibition Reduces NLRP3 Activation and Pyroptosis in Sepsis and Nerve Injury
University of RochesterBerk, Bradford39882237[39]Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS
Rensselaer Polytechnic InstitutePalermo, Edmund39793199[40]Poly(curcumin-co-poly(ethylene glycol)) films provide neuroprotection following reactive oxygen species insult in vitro
Rensselaer Polytechnic InstitutePalermo, Edmund and Gilbert, Ryan39346563[41]Pharmacology of boldine: Summary of the field and update on recent advances
Rensselaer Polytechnic InstituteGilbert, Ryanhttps://www.mdpi.com/2674-0583/2/2/10[42]Construction of an Elastin-like Polypeptide Gene in a High Copy Number Plasmid Using a Modified Method of Recursive Directional Ligation
Columbia UniversityAgrawal, Sunil38135989[43]Training Postural Balance Control with Pelvic Force Field at the Boundary of Stability
Columbia UniversityAgrawal, Sunil38486863[44]The effect of transcutaneous spinal cord stimulation on the balance and neurophysiological characteristics of young healthy adults
Columbia UniversityAgrawal, Sunil39124576[45]Effects of Robotic Postural Stand Training with Epidural Stimulation on Sitting Postural Control in Individuals with Spinal Cord Injury: A Pilot Study
City University of New York, City CollegeMartin, John H.40027669[46]Hyperreflexia after corticospinal tract lesion reflects 1A afferent circuit changes not increased KCC2 hyperexcitability
City University of New York, City CollegeMartin, John H.40060631[47]Activity Protects Spinal Premotor Interneurons from Microglial Phagocytosis and Transneuronal Degeneration After Corticospinal Injury
Bronx Veterans Medical Research Foundation, Inc.Harel, Noam Y.39040654[48]Hierarchical Bayesian estimation of motor-evoked potential recruitment curves yields accurate and robust estimates
Bronx Veterans Medical Research Foundation, Inc.Harel, Noam Y.40048825[49]Motor activity in gamma and high gamma bands recorded with a Stentrode from the human motor cortex in two people with ALS.
Bronx Veterans Medical Research Foundation, Inc.Harel, Noam Y.40313296[50]Timing-dependent synergies between noninvasive motor cortex and spinal cord stimulation in chronic cervical spinal cord injury.  
Winifred Masterson Burke Medical Research InstituteHollis, Edmund38496662[51]Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration
Icahn School of Medicine at Mount SinaiZou, Hongyan (Jenny) 38802590[52]Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
Bronx Veterans Medical Research Foundation, Inc.Harel, Noam Y.38156073[53]Transcutaneous Spinal Cord Stimulation to Stabilize Seated Systolic Blood Pressure in Persons With Chronic Spinal Cord Injury: Protocol Development
Bronx Veterans Medical Research Foundation, Inc.Harel, Noam Y.37865833[54]Remote Ischemic conditioning as an emerging tool to improve corticospinal transmission in individuals with chronic spinal cord injury
Bronx Veterans Medical Research Foundation, Inc.Harel, Noam Y.37645795[55]Timing dependent synergies between motor cortex and posterior spinal stimulation in humans
City University of NY School of Medicine; RF CUNYMartin, John H.39536089[56]Molecular signaling predicts corticospinal axon growth state and muscle response plasticity induced by neuromodulation
City University of New York, College of Staten IslandKnikou, Maria36416443[57]Physiological effects of cathodal electrode configuration for transspinal stimulation in humans
Columbia UniversityAgrawal, Sunil9925527[58]Kinematic Validation of a Robotic Exoskeleton for Assisting Seated Pelvic Movements by Wheelchair Users with Trunk Impairments
Stony Brook MedicinePuopolo, Michelino32839232[59]Contribution of CaV3.2 calcium channels drive nociceptors’ hyperexcitability and chronic neuropathic pain following spinal cord injury in mice
Icahn School of Medicine at Mount SinaiCortes, MarS1094-7159(22)01133-3[60]PO186 / #872 Short term reduction of chronic neuropathic pain after high-frequency repetitive transcranial magetic stimulation (RTMS)
Icahn School of Medicine at Mount SinaiCortes, Mar34501513[61]Pain reduction after short exposure to virtual reality environments in people with spinal cord injury
Icahn School of Medicine at Mount SinaiCortes, Mar39246648[62]Design and Validation of a Novel Robotic Neck Brace for Cervical Traction
Icahn School of Medicine at Mount SinaiIyengar, Srinivas Ravi37799971[63]A spatially specified system pharmacology therapy for axonal recovery after injury
Icahn School of Medicine at Mount SinaiIyengar, Srinivas Ravi37577656[64]Muscle-restricted Nox4 knockout partially corrects muscle contractility following spinal cord injury in mice
Icahn School of Medicine at Mount SinaiIyengar, Srinivas Ravi37692100[65]Spinal Cord Injury regulates circular RNA expression in axons
Icahn School of Medicine at Mount SinaiIyengar, Srinivas Ravi37830039[66]Memory discrimination is promoted by the expression of the transcription repressor WT1 in the dentate gyrus
Columbia UniversityAgrawal, Sunil10719943[67]Training Seated Postural Coordination in a Virtual Reality Reaching Game by Active Pelvic Guidance from a Robotic Exoskeleton
Columbia UniversityAgrawal, Sunil39358017[68]Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons
Columbia UniversityAgrawal, Sunil39792574[69]The NeuroML ecosystem for standardized multi-scale modeling in neuroscience
Columbia UniversityAgrawal, Sunil38895250[70]Mechanism of an Intrinsic Oscillation in Rat Geniculate Interneurons
Columbia UniversityAgrawal, Sunil38486972[71]A mechanism for deviance detection and contextual routing in the thalamus: a review and theoretical proposalchanism for deviance
City University of New York, College of Staten Island Knikou, Maria38656134[72]Postsynaptic potentials of soleus motor neurons produced by transspinal stimulation: a human single-motor unit study
City University of New York, College of Staten IslandKnikou, Maria38366214[73]Soleus H-reflex amplitude modulation during walking remains physiological during transspinal stimulation in humans
City University of New York, College of Staten IslandKnikou, Maria38472313[74]Tapping into the human spinal locomotor centres with transspinal stimulation
City University of New York, College of Staten IslandKnikou, Maria39034329[75]Interactions between arm and leg neuronal circuits following paired cervical and lumbosacral transspinal stimulation in healthy humans
City University of New York, College of Staten Island Knikou, Maria39841641[76]Optimal sigmoid function models for analysis of transspinal evoked potential recruitment curves recorded from different muscles
The Feinstein Institute for Medical ResearchBloom, Ona37973021[77]Editorial:  Update on current topics in spinal cord injury, trauma and rehabilitation
The Feinstein Institute for Medical ResearchBloom, Ona21311[78]Antibody levels against SARS-CoV-2 in Veterans with chronic spinal cord injury: a cross sectional analysis
The Feinstein Institute for Medical ResearchBloom, Ona40159475[79]Low intensity trans-spinal focused ultrasound reduces mechanical sensitivity and suppresses spinal microglia activation in rats with chronic constriction injury
Rensselaer Polytechnic InstituteGilbert, Ryanhttps://www.mdpi.com/2674-0583/2/2/10[80]Construction of an Elastin-like Polypeptide Gene in a High Copy Number Plasmid Using a Modified Method of Recursive Directional Ligation
Rensselaer Polytechnic InstituteGilbert, Ryan38935534[81]Delivery of TGFβ3 from magnetically responsive coaxial fibers reduces astrocyte reactivity in vitro
Rensselaer Polytechnic InstituteGilbert, Ryan39071184[82]In vitro assessment of protamine toxicity with neural cells, its therapeutic potential to counter chondroitin sulfate mediated neuron inhibition, and its effects on reactive astrocytes
Rensselaer Polytechnic InstituteGilbert, Ryan2023 BMES Annual Meeting[83]Investigating the neuroprotective potential of poly(pro-curcumin) polymers
Rensselaer Polytechnic InstituteGilbert, Ryan39793199[84]Poly(pro-curcumin-co-poly(ethylene-glycol)) films provide neuroprotection following reactive oxygen species insult in vitro
Albany Research Institute, Inc., National Center for Adaptive NeurotechnologiesWolpaw, Jonathan R.37437593[85]Methods for automated delineation and assessment of EMG responses evoked by peripheral nerve stimulation in diagnostic and closed-loop therapeutic applications
Columbia UniversityAgrawal, Sunil37155401[86]Effects of Boundary-Based Assist-as-Needed Force Field on Lower Limb Muscle Synergies During Standing Posture Training
Columbia UniversityAgrawal, Sunil36176099[87]Redistributing Ground Reaction Forces During Squatting Using a Cable-Driven Robotic Device
Columbia UniversityAgrawal, Sunil35532324[88]Robotic upright stand trainer (RobUST) and postural control in individuals with spinal cord injury
Columbia UniversityAgrawal, Sunil38515546[89]Robotic Postural Training With Epidural Stimulation for the Recovery of Upright Postural Control in Individuals With Motor Complete Spinal Cord Injury: A Pilot Study
Columbia UniversityAgrawal, Sunil38009201[90]Standing Reactive Postural Responses of Lower Limbs With and Without Self-Balance Assistance in Individuals With Spinal Cord Injury Receiving Epidural Stimulation