Dr. Styer’s research interests include the development of new molecular diagnostic tests for the detection, quantification, or characterization of bloodborne viruses and the evaluation of FDA approved diagnostic tests and diagnostic testing algorithms.

We study the structural basis of macromolecular assemblies and organelles in epithelial cells for sensing or responding to extracellular environmental changes. Our approach involves a variety of customized methods in advanced electron microscopy.

We study copy number variants (CNVs), which are widespread in the human genome and alter dosage of genes important in conditions ranging from HIV susceptibility to autism spectrum disorders. We seek to compile a catalog of CNVs and their frequencies.

Screening has uncovered individuals whose sweat chloride values are above normal, but no other CF symptoms are identified. Our aim is to determine if other variants in the CFTR gene, or modifier genes, correlate with these abnormal levels.

Dr. Totten is responsible for clinical, reference and surveillance testing for viruses and the investigation of outbreaks and emerging viral pathogens

We develop analytical methods to identify unknown chemicals in foods and environmental samples including toxic compounds and chemical terrorism agents, thus providing national surveillance of the food supply.

We study gene regulation in bacteria, with a focus on genome-scale approaches. We are interested in regulation of transcription, the function of non-coding RNAs, and leaderless translation initiation.

The Immunology Core is responsible for assisting users in flow cytometry panel development, sample acquisition, sorting, and data analysis.

The Division of Laboratory Operations oversees the Wadsworth Center's operations at five facilities in the Albany area, totaling ~900,000 square feet of space and over 210 acres of real estate.