Research Affiliate I (Post Doctoral) JR-0001897
Applications due 11/28/25
Health Research, Inc. is seeking a Research Affiliate I. This position offers a stimulating professional growth opportunity at the interface of microbiome science, metabolomics, toxicology, and human health under the mentorship of the Principal Investigator. The Research Affiliate I will work with a Principal Investigator to develop their post-doctoral research skillset by investigating how gut microbes biotransform environmental pollutants and dietary compounds, and how these microbial transformations influence pollutant toxicity and disease-relevant pathways, including carcinogenesis and systemic toxicity.
The incumbent will contribute to designing, performing, analyzing, and presenting experiments to evaluate the biological effects of microbial metabolites on human cancer cell lines, organoid models, and mouse models. Experimental approaches include cell migration, invasion, cytotoxicity, genotoxicity assays, and gene expression profiling (qPCR, RNA/DNA extraction), as well as advanced metabolomics using high-resolution mass spectrometry platforms such as QTOF and Orbitrap. The Research Affiliate I will integrate multi-omics data to elucidate mechanisms by which microbial biotransformation modulates pollutant toxicity and disease-relevant pathways. The incumbent will maintain detailed laboratory records, contribute to manuscript preparation, perform rigorous data analysis, and assist with training junior staff. The role also involves maintaining and operating key laboratory instruments and shared resources.
This position will be part of a dynamic team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come be a part of Science in the Pursuit of Health®!