Featured Publications

Dieme C, Kramer LD, Ciota AT. Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States. Parasit Vectors. 2022; 15 (1): 226. DOI: 10.1186/s13071-022-05342-3
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Dieme C, Maffei JG, Diarra M, Koetzner CA, Kuo L, Ngo KA, Dupuis Ii AP, Zink SD, Backenson PB, Kramer LD, Ciota AT. Aedes Albopictus and Cache Valley virus: a new threat for virus transmission in New York State. Emerg Microbes Infect. 2022; 11 (1): 741-748. DOI: 10.1080/22221751.2022.2044733
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Caldwell HS, Pata JD, Ciota AT. The Role of the Flavivirus Replicase in Viral Diversity and Adaptation. Viruses. 2022; 14 (5): 1076. DOI: 10.3390/v14051076
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Bialosuknia SM, Dupuis Ii AP, Zink SD, Koetzner CA, Maffei JG, Owen JC, Landwerlen H, Kramer LD, Ciota AT. Adaptive evolution of West Nile virus facilitated increased transmissibility and prevalence in New York State. Emerg Microbes Infect. 2022; 11 (1): 988-999. DOI: 10.1080/22221751.2022.2056521
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Ciota AT. Eastern Equine Encephalitis Virus Taxonomy, Genomics, and Evolution. J Med Entomol. 2022; 59 (1): 14-19. DOI: 10.1093/jme/tjab079
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Fay RL, Keyel AC, Ciota AT. West Nile virus and climate change. In: Roossinck MJ, editor. Viruses and Climate Change, Advances in Virus Research. Cambridge, MA: Academic Press. 2022; DOI: 10.1016/bs.aivir.2022.08.002
Owen JC, Landwerlen HR, Dupuis AP 2nd, Belsare AV, Sharma DB, Wang S, Ciota AT, Kramer LD. Reservoir hosts experiencing food stress alter transmission dynamics for a zoonotic pathogen. Proc Biol Sci. 2021; 288 (1956): 20210881. DOI: 10.1098/rspb.2021.0881
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Onyango MG, Lange R, Bialosuknia S, Payne A, Mathias N, Kuo L, Vigneron A, Nag D, Kramer LD, Ciota AT. Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus. Parasit Vectors. 2021; 14 (1): 573. DOI: 10.1186/s13071-021-05069-7
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Fay RL, Ngo KA, Kuo L, Willsey GG, Kramer LD, Ciota AT. Experimental Evolution of West Nile Virus at Higher Temperatures Facilitates Broad Adaptation and Increased Genetic Diversity. Viruses. 2021; 13 (10): 1889. DOI: 10.3390/v13101889
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Keyel AC, Raghavendra A, Ciota AT, Elison Timm O. West Nile virus is predicted to be more geographically widespread in New York State and Connecticut under future climate change. Glob Chang Biol. 2021; 27 (21): 5430-5445. DOI: 10.1111/gcb.15842
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Passow KT, Caldwell HS, Ngo KA, Arnold JJ, Antczak NM, Narayanan A, Jose J, Sturla SJ, Cameron CE, Ciota AT, Harki DA. A Chemical Strategy for Intracellular Arming of an Endogenous Broad-Spectrum Antiviral Nucleotide. J Med Chem. 2021; 64 (20): 15429. DOI: 10.1021/acs.jmedchem.1c01481
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Dupuis AP 2nd, Prusinski MA, O'Connor C, Maffei JG, Ngo KA, Koetzner CA, Santoriello MP, Romano CL, Xu G, Ribbe F, Campbell SR, Rich SM, Backenson PB, Kramer LD, Ciota AT. Heartland Virus Transmission, Suffolk County, New York, USA. Emerg Infect Dis. 2021; 27 (12): 3128-3132. DOI: 10.3201/eid2712.211426
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Onyango MG, Attardo GM, Kelly ET, Bialosuknia SM, Stout J, Banker E, Kuo L, Ciota AT, Kramer LD. Zika Virus Infection Results in Biochemical Changes Associated With RNA Editing, Inflammatory and Antiviral Responses in Aedes albopictus. Front Microbiol. 2020; (11): 559035. DOI: 10.3389/fmicb.2020.559035
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Gloria-Soria A, Payne AF, Bialosuknia SM, Stout J, Mathias N, Eastwood G, Ciota AT, Kramer LD, Armstrong PM. Vector Competence of Aedes albopictus Populations from the Northeastern United States for Chikungunya, Dengue, and Zika Viruses. Am J Trop Med Hyg. 2020; 104 (3): 1123-1130. DOI: 10.1186/s13071-020-04478-4
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Dieme C, Ciota AT, Kramer LD. Transmission potential of Mayaro virus by Aedes albopictus, and Anopheles quadrimaculatus from the USA. Parasit Vectors. 2020; 13 (1): 613. DOI: 10.1186/s13071-020-04478-4
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Kuo L, Jaeger AS, Banker EM, Bialosuknia SM, Mathias N, Payne AF, Kramer LD, Aliota MT, Ciota AT. Reversion to ancestral Zika virus NS1 residues increases competence of Aedes albopictus. PLoS Pathog. 2020; 16 (10): e1008951. DOI: 10.1371/journal.ppat.1008951
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Caldwell HS, Ngo K, Pata JD, Kramer LD, Ciota AT. West Nile Virus fidelity modulates the capacity for host cycling and adaptation. J Gen Virol. 2020; 101 (4): 410-419. DOI: 10.1099/jgv.0.001393
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Caldwell HS, Lasek-Nesselquist E, Follano P, Kramer LD, Ciota AT. Divergent Mutational Landscapes of Consensus and Minority Genotypes of West Nile Virus Demonstrate Host and Gene-Specific Evolutionary Pressures. Genes (Basel). 2020; 11 (11): 1299. DOI: 10.3390/genes11111299
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Onyango MG, Bialosuknia SM, Payne AF, Mathias N, Kuo L, Vigneron A, DeGennaro M, Ciota AT, Kramer LD. Increased temperatures reduce the vectorial capacity of Aedes mosquitoes for Zika virus. Emerg Microbes Infect. 2020; 9 (1): 67-77. DOI: 10.1080/22221751.2019.1707125
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Li Z, Lang Y, Sakamuru S, Samrat S, Trudeau N, Kuo L, Rugenstein N, Tharappel A, D'Brant L, Koetzner CA, Hu S, Zhang J, Huang R, Kramer LD, Butler D, Xia M, Li H. Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo. Emerg Microbes Infect. 2020; 20 1-37. DOI: 10.1080/22221751.2020.1838954
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Li Z, Xu J, Lang Y, Fan X, Kuo L, D'Brant L, Hu S, Samrat SK, Trudeau N, Tharappel AM, Rugenstein N, Koetzner CA, Zhang J, Chen H, Kramer LD, Butler D, Zhang QY, Zhou J, Li H. JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo. ACS Infect Dis. 2020; 6 (10): 2616-2628. DOI: 10.1021/acsinfecdis.0c00217
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Bialosuknia SM, Tan Y, Zink SD, Koetzner CA, Maffei JG, Halpin RA, Muller E, Novatny M, Shilts M, Fedorova NB, Amedeo P, Das SR, Pickett B, Kramer LD, Ciota AT. Evolutionary dynamics and molecular epidemiology of West Nile virus in New York State: 1999-2015. Virus Evol. 2019; 5 (2): vez020. DOI: 10.1093/ve/vez020
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Ciota AT, Keyel AC. The Role of Temperature in Transmission of Zoonotic Arboviruses. Viruses. 2019; 11 (11): 1013. DOI: 10.3390/v11111013
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Kim SY, Koetzner CA, Payne AF, Nierode GJ, Yu Y, Wang R, Barr E, Dordick JS, Kramer LD, Zhang F, Linhardt RJ. Glycosaminoglycan Compositional Analysis of Relevant Tissues in Zika Virus Pathogenesis and in Vitro Evaluation of Heparin as an Antiviral against Zika Virus Infection. Biochemistry. 2019; 58 (8): 1155-1166. DOI: 10.1021/acs.biochem.8b01267
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Tan Y, Lam TT, Heberlein-Larson LA, Smole SC, Auguste AJ, Hennigan S, Halpin RA, Fedorova N, Puri V, Stockwell TB, Shilts MH, Andreadis T, Armstrong PM, Tesh RB, Weaver SC, Unnasch TR, Ciota AT, Kramer LD, Das SR. Large-Scale Complete-Genome Sequencing and Phylodynamic Analysis of Eastern Equine Encephalitis Virus Reveals Source-Sink Transmission Dynamics in the United States. J Virol. 2018; 92 (12): e00074-18. DOI: 10.1128/JVI.00074-18
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Ciota AT, Chin PA, Ehrbar DJ, Micieli MV, Fonseca DM, Kramer LD. Differential Effects of Temperature and Mosquito Genetics Determine Transmissibility of Arboviruses by Aedes aegypti in Argentina. Am J Trop Med Hyg. 2018; 99 (2): 417-424. DOI: 10.4269/ajtmh.18-0097
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Ciota AT, Bialosuknia SM, Zink SD, Brecher M, Ehrbar DJ, Morrissette MN, Kramer LD. Effects of Zika Virus Strain and Aedes Mosquito Species on Vector Competence. Emerging Infectious Diseases. 2017; 23 (7): 1110-1117.
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Ciota AT, Bialosuknia SM, Ehrbar DJ, Kramer LD. Vertical Transmission of Zika Virus by Aedes aegypti and Ae. albopictus Mosquitoes. Emerg Infect Dis. 2017; 23 (5): 880-882. DOI: 10.3201/eid2305.162041
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Frost HM, Schotthoefer AM, Thomm AM, Dupuis AP 2nd, Kehl SC, Kramer LD, Fritsche TR, Harrington YA, Knox KK. Serologic Evidence of Powassan Virus Infection in Patients with Suspected Lyme Disease. Emerg Infect Dis. 2017; 23 (8): 1384-1388. DOI: 10.3201/eid2308.161971
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Van Slyke GA, Arnold JJ, Lugo AJ, Griesemer SB, Moustafa IM, Kramer LD, Cameron CE, Ciota AT. Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes. PLoS Pathogens. 2015; 11 (6): e1005009.
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Ciota AT, Matacchiero AC, Kilpatrick AM, Kramer LD. The effect of temperature on life history traits of Culex mosquitoes. Parasite Vectors. 2014; 51 (1): 55-62.
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Aliota MT, Dupuis AP, Wilczek MP, Peters RJ, Ostfeld RS, Kramer LD. The Prevalence of Zoonotic Tick-Borne Pathogens in Ixodes Scapularis Collected in the Hudson Valley, New York State. Vector Borne Zoonotic Diseases. 2014; 14 (4): 245-250.
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Kilpatrick AM, Peters RJ, Dupuis AP, Jones MJ, Daszak P, Marra PP, Kramer LD. Predicted and observed mortality from vector-borne disease in wildlife: West Nile virus and small songbirds. Biological Conservation. 2013; 165 79-85.
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Ciota AT, Chin PA, Kramer LD. The effect of hybridization of Culex pipiens complex mosquitoes on transmission of West Nile virus. Parasite Vectors. 2013; 6 (1): 305.
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Dupuis AP, Peters RJ, Prusinski MA, Falco RC, Ostfeld RS, Kramer LD. Isolation of deer tick virus (Powassan virus, lineage II) from Ixodes scapularis and detection of antibody in vertebrate hosts sampled in the Hudson Valley, New York State. Parasite & Vectors. 2013; (6): 185.
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Ciota AT, Ehrbar DJ, Van Slyke GA, Payne AF, Willsey GG, Viscio RE, Kramer LD. Quantification of intrahost bottlenecks of West Nile virus in Culex pipiens mosquitoes using an artificial mutant swarm. Infection, Genetics & Evolution. 2012; 12 (3): 557-564.
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Ciota AT, Styer LM, Meola MA and Kramer LD. The costs of infection and resistance as determinants of West Nile virus susceptibility in Culex mosquitoes. BMC Ecology. 2011; (11): 23.
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Kilpatrick, AM, Fonseca, DM, Ebel, GD, Reddy, MR and Kramer, LD. Spatial and Temporal Variation in Vector Competence of Culex pipiens and Cx. restuans Mosquitoes for West Nile Virus. American Journal of Tropical Medicine & Hygiene. 2010; 83 (3): 607-613.
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