Refeyn TwoMP Mass Photometer with MassFluidix HC add on

Two MP

www.refeyn.com

For measuring protein:protein and nucleic acid:protein interactions

  • Accurately measures the mass distribution of individual biomolecules in solution

  • Label free

  • Non-destructive

  • Minimal volume

  • Weak interactions can be measured using the MassFluidix HC add on unit that dilutes sample in ~37 mS

 

Exciting Instruments EI-FLEX

EI-FLEX

https://excitinginstruments.com 

Single molecule fluorescence spectrometer for smFRET and fluorescence correlation spectroscopy for measuring

  • Protein and nucleic acid interactions

  • Dynamic protein conformational landscapes

  • Binding and diffusion rates, including protein:protein and protein:ligand binding

  • All performed in solution without surface immobilization

Cytiva Biacore T200

Biacore

Surface plasmon resonance measures molecular interactions in real time with a wide range of applications

  • Binding kinetics ka and kd

  • Equilibrium Binding affinity KA

  • Concentration analysis

 

Cytiva Akta Pure M25

Cytiva Akta Pure

For preparative and analytical column chromatography

  • Flow rate 0.001-25 mL/min

  • Monitor up to 3 wavelengths (190-700 nm)

  • 4 inlet valves

  • 5 column positions with reverse flow to allow scouting or multiple column chromatography

  • Fraction collector 9-T allows for 0.02-50 mL Fractions

  • Sample pump

  • pH meter

  • Multiple columns for affinity, ion exchange, hydrophobic interaction and size exclusion chromatography

  • Many accessories 

 

Molecular Devices Spectramax M2 Plate reader

M2 Plate Reader

Thermo Scientific Nanodrop Lite Plus

Nanodrop

Measures purified protein, DNA, and RNA

  • Fast accurate measurements using 1-2 µL of sample

Beckman DU640 UV/VIS Spectroscopy

Beckman Spectroscopy

Equipped with software packages for measuring proteins, nucleic acids and performing kinetics

  • Peltier temperature control 

  • Accessories include microcells for small volumes

 

Bio-Rad 2-D gel electrophoresis equipment

Protean IEF cell for 7, 11,17,18 and 24 cm immobilized pH gradient strips

Protean IEF

 

Mini-PROTEAN and Mini Trans-Blot cells 

MiniProtean

 

 

Criterion and Criterion Blotter cells

Criterion

 

PROTEAN II and PROTEAN II XL cells 

Biorad Large Format

 

 

Chemidoc XRS+ for gel imaging and densitometry of color, fluorescence, and chemiluminescence

Gel Imager