Featured Publications

Sankar P, Ramos RB, Corro J, Mishra LK, Nafiz TN, Bhargavi G, Saqib M, Poswayo SKL, Parihar SP, Cai Y, Subbian S, Ojha AK, Mishra BB. Fatty acid metabolism in neutrophils promotes lung damage and bacterial replication during tuberculosis. PLoS Pathog. 2024; Oct 4;20 (10): e1012188. DOI: 10.1371/journal.ppat.1012188
Li Y, Majumdar S, Treen R, Sharma MR, Corro J, Gamper HB, Manjari SR, Prusa J, Banavali NK, Stallings CL, Hou YM, Agrawal RK, Ojha AK. Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation. Proc Natl Acad Sci U S A. 2023; May 30;120 (22): e2302006120. DOI: 10.1073/pnas.2302006120
Hurst-Hess K, Walz A, Yang Y, McGuirk H, Gonzalez-Juarrero M, Hatfull GF, Ghosh P, Ojha AK. Intrapulmonary Treatment with Mycobacteriophage LysB Rapidly Reduces Mycobacterium abscessus Burden. Antimicrob Agents Chemother. 2023; Jun 15;67 (6): e0016223. DOI: 10.1128/aac.00162-23
Li Y, Sharma MR, Koripella RK, Banavali NK, Agrawal RK, Ojha AK. Ribosome hibernation: a new molecular framework for targeting nonreplicating persisters of mycobacteria. Microbiology. 2021; 167 (2): 001035. DOI: 10.1099/mic.0.001035
Li Y, Corro JH, Palmer CD, Ojha AK. Progression from remodeling to hibernation of ribosomes in zinc-starved mycobacteria. Proc Natl Acad Sci U S A. 2020; DOI: 10.1073/pnas.2013409117
Richards JP, Cai W, Zill NA, Zhang W, Ojha AK. Adaptation of Mycobacterium tuberculosis to Biofilm Growth Is Genetically Linked to Drug Tolerance. Antimicrob Agents Chemother. 2019; 63 (11): e01213-19.
Li Y, Sharma MR, Koripella RK, Yang Y, Kaushal PS, Lin Q, Wade JT, Gray TA, Derbyshire KM, Agrawal RK, Ojha AK. Zinc depletion induces ribosome hibernation in mycobacteria. Proc. Natl. Acad. Sci. USA. 2018; Jul 23 (pii: 201804555):