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Paczkowski Laboratory Publications

A more complete list of publications is available.

Paczkowski Laboratory		Feathers JR, Richael EK, Simanek KA, Fromme JC, Paczkowski JE. Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation. Structure. 2022;30(12):1626-1636. DOI: 10.1016/j.str.2022.10.008 Pubmed Web Address Simanek KA, Paczkowski JE. Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance. Microorganisms. 2022;10(6):1247. DOI: 10.3390/microorganisms10061247 Pubmed Web Address Simanek KA, Taylor IR, Richael EK, Lasek-Nesselquist E, Bassler BL, Paczkowski JE. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa. Microbiol Spectr. 2022;10(1):e0210821. DOI: 10.1128/spectrum.02108-21 Pubmed Web Address Taylor IR, Paczkowski JE, Jeffrey PD, Henke BR, Smith CD, Bassler BL. Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. ACS Chem Biol. 2021;16(4):740-752. DOI: 10.1021/acschembio.1c00049 Pubmed Web Address

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