Skip to main content

You are here

Research & Development

Research Projects:

  • Expand use of targeted next generation sequencing in clinical parasitology
  • Develop digital droplet PCR assays for quantitative testing of bloodborne parasites
  • Develop RNA-based detection assays, such as transcription-mediated amplification for increased sensitivity and multiplex detection of parasites in complex specimens
  • Evaluate molecular testing of dried blood spots for the detection of Plasmodium
  • Develop a comprehensive set of conventional PCR and sequencing primers sequencing to aid in identification of helminth specimens

Parasitology

  • Clemons B, Barratt J, Lane M, Qvarnstrom Y, Teal AE, Zayas G, Madison-Antenucci S. Assessing an Adaptation of the Universal Parasite Diagnostic Assay for Bloodborne Parasites in a US State Public Health Laboratory. Am J Trop Med Hyg. 2021;106(2):671-677. DOI: 10.4269/ajtmh.21-0707
  • Pubmed Web Address

  • Mergen K, Espina N, Teal A, Madison-Antenucci S. Detecting Cryptosporidium in Stool Samples Submitted to a Reference Laboratory. Am J Trop Med Hyg. 2020;103(1):421-427. DOI: 10.4269/ajtmh.19-0792
  • Pubmed Web Address

  • Madison-Antenucci S, Wormser GP, Levin AE, Wong SJ. Frequency and magnitude of seroreactivity to Babesia microti in 245 patients diagnosed by PCR in New York State. Diagn Microbiol Infect Dis. 2020;97(1):115008. DOI: 10.1016/j.diagmicrobio.2020.115008
  • Pubmed Web Address

  • Alleyne L, Fitzhenry R, Mergen KA, Espina N, Amoroso E, Cimini D, Balter S, Fireteanu AM, Seeley A, Janus L, Gutelius B, Madison-Antenucci S, Thompson CN. Epidemiology of Cryptosporidiosis, New York City, New York, USA, 1995-2018. Emerg Infect Dis. 2020;26(3):409-19. DOI: 10.3201/eid2603.190785
  • Pubmed Web Address

  • Madison-Antenucci S, Kramer LD, Gebhardt LL, Kauffman E. Emerging Tick-Borne Diseases. Clin Microbiol Rev. 2020;32(2):e00083-18. DOI: 10.1128/CMR.00083-18
  • Pubmed Web Address

  • Talundzic E, Ravishankar S, Kelley J, Patel D, Plucinski M, Schmedes S, Ljolje D, Clemons B, Madison-Antenucci S, Arguin PM, Lucchi NW, Vannberg F, Udhayakumar V. Next-Generation Sequencing and Bioinformatics Protocol for Malaria Drug Resistance Marker Surveillance. Antimicrob Agents Chemother. 2018;62(4):e02474-17. DOI: 10.1128/AAC.02474-17
  • Pubmed Web Address

  • Roellig DM, Yoder JS, Madison-Antenucci S, Robinson TJ, Van TT, Collier SA, Boxrud D, Monson T, Bates LA, Blackstock AJ, Shea S, Larson K, Xiao L, Beach M. Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing. PLoS One. 2017;12(1):e0169915. DOI: 10.1371/journal.pone.0169915
  • Pubmed Web Address

  • Madison-Antenucci S, Relich RF, Doyle L, Espina N, Fuller D, Karchmer T, Lainesse A, Mortensen JE, Pancholi P, Veros W, Harrington SM. Multicenter Evaluation of BD Max Enteric Parasite Real-Time PCR Assay for Detection of Giardia duodenalis, Cryptosporidium hominis, Cryptosporidium parvum, and Entamoeba histolytica. J Clin Microbiol. 2016;54(11):2681-2688. DOI: 10.1128/JCM.00765-16
  • Pubmed Web Address

  • Hashem Y, Georges AD, Fu J, Buss SN, Jossinet F, Jobe A, Zhang Q, Liao HY, Grassucci RA, Bajaj C, Westhof E, Madison-Antenucci S, Frank J. High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome. Nature. 2013;494(7437):385-389. DOI:
  • Pubmed Web Address

  • Teal AE, Habura A, Ennis J, Keithly JS, Madison-Antenucci S. A New Real-Time PCR Assay for Improved Detection of the Parasite Babesia microti. Journal of Clinical Microbiology. 2012;50(3):903-908. DOI:
  • Pubmed Web Address

  • Joseph JT, Purtill K, Wong SJ, Munoz J, Teal A, Madison-Antenucci S, Horowitz HW, Aguero-Rosenfeld ME, Moore JM, Abramowsky C, Wormser GP. Vertical transmission of Babesia microti, United States. Emerging Infectious Diseases. 2012;18(8):1318-1321. DOI:
  • Read More
  • Pubmed Web Address

  • Ennis JG, Teal AE, Habura A, Madison-Antenucci S, Keithly JS, Arguin PM, Barnwell JW, Collins WE, Mali S, Slutsker L, Dasilva A, Hwang J. Simian Malaria in a U.S. Traveler -- New York. Morbidity and Mortality Weekly Report . 2008;58(9):229-232. DOI:
  • Read More

  • Hans J, Hajduk SL, Madison-Antenucci S. RNA-editing-associated Protein 1 Null Mutant Reveals Link to Mitochondrial RNA Stability. RNA. 2007;13(6):881-889. DOI:
  • Pubmed Web Address

  • Cirino NM, Tavakoli NP, Madison-Antenucci S, Egan C. Multiplex rtPCR in Microbiology. Real Time PCR in Microbiology: From Diagnosis to Characterization. Caister Academic Press. 2007; DOI:
  • Read More